Matthew Lillard has been cast with Cooper Koch and Amber Midthunder in new thriller Rot.

The trio will star in the upcoming psychological thriller and body horror from Alexandra Magistro, an executive at Mike Flanagan's Red Room Pictures.

As reported by Deadline, Koch, Midthunder and Lillard have all joined the cast for Magistro's feature directorial debut.

The film comes from a 2024 Black List script by Geo Bradley, who describes the story as "Repulsion by why of Cronenberg".

No official logline has been given, but the Black List reveals: "[Rot] follows an antisocial man suffering from obsessive compulsions who is haunted by the death of his hoarder mother.

"The man takes on work as a trauma cleaner in hopes of facing his past, but the job soon begins to infest and unravel his mental state."

Production for the film is set to get underway in November in Vancouver.

Lillard has worked with Flanagan before, having appeared in The Life of Chuck, while his recent credits include Scream 7, Daredevil: Born Again, and Five Nights at Freddy's 2.

He is also set to appear in Superman: Man of Tomorrow.

Midthunder is best known for her starring role in Prey, and she has also appeared in Novocaine and Monarch: Legacy of Monsters.

Both she and Lillard are also appearing in Flanagan's upcoming adaptation of Stephen King's Carrie for Amazon Prime Video, which is set to drop next month.

Meanwhile, Koch earned plaudits for his role as Erik Menendez in Ryan Murphy's Monsters: The Lyle and Erik Menendez Story for Netflix.

His next role will be in Luca Guadagnino's drama Artificial, which stars Andrew Garfield as OpenAI founder Sam Altman.

Lillard rose to fame as Stu Macher in 1996's Scream before playing Shaggy in 2002's Scooby-Doo and its sequel Monsters Unleashed two years later, while he has found a new fanbase since playing William Afton in Five Nights At Freddy's in 2023.

Speaking to the Phase Hero podcast earlier this year, Lillard admitted he believes a new wave of fan nostalgia has given him a career reboot.

He said: "Scooby-Doo 1 and 2 are more popular now than they ever were when they came out.

"So I do think there's a weird nostalgia thing happening in our industry and in the zeitgeist because I think that people are longing for ye olde times.

"I think that's one of the reasons I'm having this moment to be honest, is because I was identified in that moment, so people are hiring me again."

He argued that movie fans "miss the old times" rather than him as an actor, adding: "I think that's why I'm working. I don't think anyone really likes me. They just miss the old times."